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Potentiation of Hydrogen Peroxide Toxicity: From Catalase Inhibition to Stable DNA-iron Complexes

Hydrogen peroxide (H(2)O(2)) is unique among general toxins, because it is stable in abiotic environments at ambient temperature and neutral pH, yet rapidly kills any type of cells by producing highly-reactive hydroxyl radicals. This life-specific reactivity follows distribution of soluble iron, Fe(...

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書目詳細資料
發表在:Mutat Res
Main Authors: Mahaseth, Tulip, Kuzminov, Andrei
格式: Artigo
語言:Inglês
出版: 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607474/
https://ncbi.nlm.nih.gov/pubmed/28927535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrrev.2016.08.006
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