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Potentiation of Hydrogen Peroxide Toxicity: From Catalase Inhibition to Stable DNA-iron Complexes

Hydrogen peroxide (H(2)O(2)) is unique among general toxins, because it is stable in abiotic environments at ambient temperature and neutral pH, yet rapidly kills any type of cells by producing highly-reactive hydroxyl radicals. This life-specific reactivity follows distribution of soluble iron, Fe(...

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Dettagli Bibliografici
Pubblicato in:Mutat Res
Autori principali: Mahaseth, Tulip, Kuzminov, Andrei
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607474/
https://ncbi.nlm.nih.gov/pubmed/28927535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrrev.2016.08.006
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