Th17-Mediated Cross Protection against Pneumococcal Carriage by Vaccination with a Variable Antigen

Serotype-specific protection against Streptococcus pneumoniae is an important limitation of the current polysaccharide-based vaccines. To prevent serotype replacement, reduce transmission, and limit the emergence of new variants, it is essential to induce broad protection and restrict pneumococcal c...

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Udgivet i:Infect Immun
Main Authors: Kuipers, Kirsten, Jong, Wouter S. P., van der Gaast-de Jongh, Christa E., Houben, Diane, van Opzeeland, Fred, Simonetti, Elles, van Selm, Saskia, de Groot, Ronald, Koenders, Marije I., Azarian, Taj, Pupo, Elder, van der Ley, Peter, Langereis, Jeroen D., Zomer, Aldert, Luirink, Joen, de Jonge, Marien I.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Microbial Immunity and Vaccines
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607416/
https://ncbi.nlm.nih.gov/pubmed/28717032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00281-17
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