Th17-Mediated Cross Protection against Pneumococcal Carriage by Vaccination with a Variable Antigen

Serotype-specific protection against Streptococcus pneumoniae is an important limitation of the current polysaccharide-based vaccines. To prevent serotype replacement, reduce transmission, and limit the emergence of new variants, it is essential to induce broad protection and restrict pneumococcal c...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Kuipers, Kirsten, Jong, Wouter S. P., van der Gaast-de Jongh, Christa E., Houben, Diane, van Opzeeland, Fred, Simonetti, Elles, van Selm, Saskia, de Groot, Ronald, Koenders, Marije I., Azarian, Taj, Pupo, Elder, van der Ley, Peter, Langereis, Jeroen D., Zomer, Aldert, Luirink, Joen, de Jonge, Marien I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607416/
https://ncbi.nlm.nih.gov/pubmed/28717032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00281-17
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