Th17-Mediated Cross Protection against Pneumococcal Carriage by Vaccination with a Variable Antigen

Serotype-specific protection against Streptococcus pneumoniae is an important limitation of the current polysaccharide-based vaccines. To prevent serotype replacement, reduce transmission, and limit the emergence of new variants, it is essential to induce broad protection and restrict pneumococcal c...

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Dettagli Bibliografici
Pubblicato in:Infect Immun
Autori principali: Kuipers, Kirsten, Jong, Wouter S. P., van der Gaast-de Jongh, Christa E., Houben, Diane, van Opzeeland, Fred, Simonetti, Elles, van Selm, Saskia, de Groot, Ronald, Koenders, Marije I., Azarian, Taj, Pupo, Elder, van der Ley, Peter, Langereis, Jeroen D., Zomer, Aldert, Luirink, Joen, de Jonge, Marien I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
Soggetti:
Microbial Immunity and Vaccines
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607416/
https://ncbi.nlm.nih.gov/pubmed/28717032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00281-17
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