Th17-Mediated Cross Protection against Pneumococcal Carriage by Vaccination with a Variable Antigen

Serotype-specific protection against Streptococcus pneumoniae is an important limitation of the current polysaccharide-based vaccines. To prevent serotype replacement, reduce transmission, and limit the emergence of new variants, it is essential to induce broad protection and restrict pneumococcal c...

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Vydáno v:Infect Immun
Hlavní autoři: Kuipers, Kirsten, Jong, Wouter S. P., van der Gaast-de Jongh, Christa E., Houben, Diane, van Opzeeland, Fred, Simonetti, Elles, van Selm, Saskia, de Groot, Ronald, Koenders, Marije I., Azarian, Taj, Pupo, Elder, van der Ley, Peter, Langereis, Jeroen D., Zomer, Aldert, Luirink, Joen, de Jonge, Marien I.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
Microbial Immunity and Vaccines
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607416/
https://ncbi.nlm.nih.gov/pubmed/28717032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00281-17
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