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From microbial gene essentiality to novel antimicrobial drug targets

BACKGROUND: Bacterial respiratory tract infections, mainly caused by Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis are among the leading causes of global mortality and morbidity. Increased resistance of these pathogens to existing antibiotics necessitates the search for...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Mobegi, Fredrick M, van Hijum, Sacha AFT, Burghout, Peter, Bootsma, Hester J, de Vries, Stefan PW, Jongh, Christa E van der Gaast-de, Simonetti, Elles, Langereis, Jeroen D, Hermans, Peter WM, de Jonge, Marien I, Zomer, Aldert
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233050/
https://ncbi.nlm.nih.gov/pubmed/25373505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-958
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