Tumor-associated B-cells induce tumor heterogeneity and therapy resistance

In melanoma, therapies with inhibitors to oncogenic BRAF(V600E) are highly effective but responses are often short-lived due to the emergence of drug-resistant tumor subpopulations. We describe here a mechanism of acquired drug resistance through the tumor microenvironment, which is mediated by huma...

Szczegółowa specyfikacja

Zapisane w:
Opis bibliograficzny
Wydane w:Nat Commun
Główni autorzy: Somasundaram, Rajasekharan, Zhang, Gao, Fukunaga-Kalabis, Mizuho, Perego, Michela, Krepler, Clemens, Xu, Xiaowei, Wagner, Christine, Hristova, Denitsa, Zhang, Jie, Tian, Tian, Wei, Zhi, Liu, Qin, Garg, Kanika, Griss, Johannes, Hards, Rufus, Maurer, Margarita, Hafner, Christine, Mayerhöfer, Marius, Karanikas, Georgios, Jalili, Ahmad, Bauer-Pohl, Verena, Weihsengruber, Felix, Rappersberger, Klemens, Koller, Josef, Lang, Roland, Hudgens, Courtney, Chen, Guo, Tetzlaff, Michael, Wu, Lawrence, Frederick, Dennie Tompers, Scolyer, Richard A., Long, Georgina V., Damle, Manashree, Ellingsworth, Courtney, Grinman, Leon, Choi, Harry, Gavin, Brian J., Dunagin, Margaret, Raj, Arjun, Scholler, Nathalie, Gross, Laura, Beqiri, Marilda, Bennett, Keiryn, Watson, Ian, Schaider, Helmut, Davies, Michael A., Wargo, Jennifer, Czerniecki, Brian J., Schuchter, Lynn, Herlyn, Dorothee, Flaherty, Keith, Herlyn, Meenhard, Wagner, Stephan N.
Format: Artigo
Język:Inglês
Wydane: Nature Publishing Group UK 2017
Hasła przedmiotowe:
Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605714/
https://ncbi.nlm.nih.gov/pubmed/28928360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00452-4
Etykiety: Dodaj etykietę
Nie ma etykietki, Dołącz pierwszą etykiete!

Podobne zapisy