Galpha(13) mediates human cytomegalovirus-encoded chemokine receptor US28 induced cell death in melanoma

US28, a constitutively active G-protein-coupled receptor encoded by the human cytomegalovirus, leads to mechanistically unknown programmed cell death. Here we show that expression of wild type US28 in human melanoma cells leads to apoptotic cell death via caspase 3 activation along with reduced cell...

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Bibliographic Details
Published in:Int J Cancer
Main Authors: Joshi, Shripad, Wels, Christian, Beham-Schmid, Christine, Fukunaga-Kalabis, Mizuho, Holmen, Sheri L., Otte, Marcus, Herlyn, Meenhard, Waldhoer, Maria, Schaider, Helmut
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496263/
https://ncbi.nlm.nih.gov/pubmed/25754407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29506
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