High-magnitude compression accelerates the premature senescence of nucleus pulposus cells via the p38 MAPK-ROS pathway

BACKGROUND: Mechanical overloading can lead to disc degeneration. Nucleus pulposus (NP) cell senescence is aggravated within the degenerated disc. This study was designed to investigate the effects of high compression on NP cell senescence and the underlying molecular mechanism of this process. METH...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Arthritis Res Ther
Autores principales: Li, Pei, Hou, Gang, Zhang, Ruijie, Gan, Yibo, Xu, Yuan, Song, Lei, Zhou, Qiang
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604423/
https://ncbi.nlm.nih.gov/pubmed/28923094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-017-1384-z
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares