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Role of p38–MAPK pathway in the effects of high-magnitude compression on nucleus pulposus cell senescence in a disc perfusion culture

Nucleus pulposus (NP) cell senescence is a typical pathological feature within the degenerative intervertebral disc. As a potential inducing and aggregating factor of disc degeneration, mechanical overloading affects disc biology in multiple ways. The present study was to investigate the NP cell sen...

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Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: Pang, Lianglong, Li, Pei, Zhang, Ruijie, Xu, Yuan, Song, Lei, Zhou, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5635211/
https://ncbi.nlm.nih.gov/pubmed/28620118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20170718
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