Identification by Site-directed Mutagenesis of Residues Involved in Ligand Recognition and Activation of the Human A(3) Adenosine Receptor

Ligand recognition has been extensively explored in G protein-coupled A(1), A(2A), and A(2B) adenosine receptors but not in the A(3) receptor, which is cerebroprotective and cardioprotective. We mutated several residues of the human A(3) adenosine receptor within transmembrane domains 3 and 6 and th...

Full description

Saved in:
Bibliographic Details
Published in:J Biol Chem
Main Authors: Gao, Zhan-Guo, Chen, Aishe, Barak, Dov, Kim, Soo-Kyung, Müller, Christa E., Jacobson, Kenneth A.
Format: Artigo
Language:Inglês
Published: 2002
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602557/
https://ncbi.nlm.nih.gov/pubmed/11891221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110960200
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items