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Identification of Essential Residues Involved in the Allosteric Modulation of the Human A(3) Adenosine Receptor

We examined the effects on allosteric modulation and ligand binding of the mutation of amino acid residues of the human A(3) adenosine receptor (A(3)AR) that are hypothesized to be near one of three loci: the putative sodium binding site, the putative ligand binding site, and the DRY motif in transm...

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Detalhes bibliográficos
Publicado no:Mol Pharmacol
Main Authors: GAO, ZHAN-GUO, KIM, SOO-KYUNG, GROSS, ARIEL S., CHEN, AISHE, BLAUSTEIN, JOSHUA B., JACOBSON, KENNETH A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367541/
https://ncbi.nlm.nih.gov/pubmed/12695530
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