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Identification by Site-directed Mutagenesis of Residues Involved in Ligand Recognition and Activation of the Human A(3) Adenosine Receptor

Ligand recognition has been extensively explored in G protein-coupled A(1), A(2A), and A(2B) adenosine receptors but not in the A(3) receptor, which is cerebroprotective and cardioprotective. We mutated several residues of the human A(3) adenosine receptor within transmembrane domains 3 and 6 and th...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Gao, Zhan-Guo, Chen, Aishe, Barak, Dov, Kim, Soo-Kyung, Müller, Christa E., Jacobson, Kenneth A.
Format: Artigo
Jezik:Inglês
Izdano: 2002
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602557/
https://ncbi.nlm.nih.gov/pubmed/11891221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110960200
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