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Identification by Site-directed Mutagenesis of Residues Involved in Ligand Recognition and Activation of the Human A(3) Adenosine Receptor

Ligand recognition has been extensively explored in G protein-coupled A(1), A(2A), and A(2B) adenosine receptors but not in the A(3) receptor, which is cerebroprotective and cardioprotective. We mutated several residues of the human A(3) adenosine receptor within transmembrane domains 3 and 6 and th...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Gao, Zhan-Guo, Chen, Aishe, Barak, Dov, Kim, Soo-Kyung, Müller, Christa E., Jacobson, Kenneth A.
Format: Artigo
Idioma:Inglês
Publicat: 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602557/
https://ncbi.nlm.nih.gov/pubmed/11891221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110960200
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