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CONSTITUTIVE ACTIVATION OF A(3) ADENOSINE RECEPTORS BY SITE-DIRECTED MUTAGENESIS
The objective of this study was to create constitutively active mutant human A(3) adenosine receptors (ARs) using single amino acid replacements, based on findings from other G protein-coupled receptors. A(3) ARs mutated in transmembrane helical domains (TMs) 1, 3, 6, and 7 were expressed in COS-7 c...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2001
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3626079/ https://ncbi.nlm.nih.gov/pubmed/11396942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1006/bbrc.2001.5027 |
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