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NUCLEOSIDE MODIFICATION AND CONCERTED MUTAGENESIS OF THE HUMAN A(3) ADENOSINE RECEPTOR TO PROBE INTERACTIONS BETWEEN THE 2-POSITION OF ADENOSINE ANALOGS AND Gln(167) IN THE SECOND EXTRACELLULAR LOOP
Residues of the second extracellular loop are believed to be important for ligand recognition in adenosine receptors. Molecular modeling studies have suggested that one such residue, Gln(167) of the human A(3) receptor, is in proximity to the C2 moiety of some adenosine analogs when bound. Here this...
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| Publicado no: | Nucleosides Nucleotides Nucleic Acids |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6954878/ https://ncbi.nlm.nih.gov/pubmed/16438031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15257770500265778 |
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