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(N)-Methanocarba 2,N(6)-Disubstituted Adenine Nucleosides as Highly Potent and Selective A3 Adenosine Receptor Agonists
A series of ring-constrained (N)-methanocarba-5′-uronamide 2,N(6)-disubstituted adenine nucleosides have been synthesized via Mitsunobu condensation of the nucleobase precursor with a pseudosugar ring containing a 5′-ester functionality. Following appropriate functionalization of the adenine ring, t...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3463111/ https://ncbi.nlm.nih.gov/pubmed/15771421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm049580r |
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