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Site-directed Mutagenesis Identifies Residues Involved in Ligand Recognition in the Human A(2a) Adenosine Receptor
The A(2a) adenosine receptor is a member of the G-protein coupled receptor family, and its activation stimulates cyclic AMP production. To determine the residues which are involved in ligand binding, several residues in transmembrane domains 5–7 were individually replaced with alanine and other amin...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
1995
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3427751/ https://ncbi.nlm.nih.gov/pubmed/7775460 |
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