Hydrophilic Side Chains in the Third and Seventh Transmembrane Helical Domains of Human A(2A) Adenosine Receptors Are Required for Ligand Recognition

Hydrophilic residues of the G protein-coupled human A(2A) adenosine receptor that are potentially involved in the binding of the ribose moiety of adenosine were targeted for mutagenesis. Residues in a T(88)QSS(91) sequence in the third transmembrane helical domain (TM3) were individually replaced wi...

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מידע ביבליוגרפי
Main Authors: JIANG, QIAOLING, VAN RHEE, A. MICHIEL, KIM, JEONGHO, YEHLE, SUSAN, WESS, JüRGEN, JACOBSON, KENNETH A.
פורמט: Artigo
שפה:Inglês
יצא לאור: 1996
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Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418326/
https://ncbi.nlm.nih.gov/pubmed/8794889
תגים: הוספת תג
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