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A Specific Interface between Integrin Transmembrane Helices and Affinity for Ligand

Conformational communication across the plasma membrane between the extracellular and intracellular domains of integrins is beginning to be defined by structural work on both domains. However, the role of the α and β subunit transmembrane domains and the nature of signal transmission through these d...

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Bibliographic Details
Main Authors: Luo, Bing-Hao, Springer, Timothy A, Takagi, Junichi
Format: Artigo
Language:Inglês
Published: Public Library of Science 2004
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC423134/
https://ncbi.nlm.nih.gov/pubmed/15208712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0020153
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