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Structure of integrin α(5)β(1) in complex with fibronectin

The membrane-distal headpiece of integrins has evolved to specifically bind large extracellular protein ligands, but the molecular architecture of the resulting complexes has not been determined. We used molecular electron microscopy to determine the three-dimensional structure of the ligand-binding...

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Detalhes bibliográficos
Main Authors: Takagi, Junichi, Strokovich, Konstantin, Springer, Timothy A., Walz, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC212714/
https://ncbi.nlm.nih.gov/pubmed/12970173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg445
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