Structure of integrin α(5)β(1) in complex with fibronectin

The membrane-distal headpiece of integrins has evolved to specifically bind large extracellular protein ligands, but the molecular architecture of the resulting complexes has not been determined. We used molecular electron microscopy to determine the three-dimensional structure of the ligand-binding...

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Publié dans:	EMBO J
Auteurs principaux:	Takagi, Junichi, Strokovich, Konstantin, Springer, Timothy A., Walz, Thomas
Format:	Artigo
Langue:	Inglês
Publié:	Nature Publishing Group 2003
Sujets:	Articles
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC212714/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12970173/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg445
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