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Structure of integrin α(5)β(1) in complex with fibronectin

The membrane-distal headpiece of integrins has evolved to specifically bind large extracellular protein ligands, but the molecular architecture of the resulting complexes has not been determined. We used molecular electron microscopy to determine the three-dimensional structure of the ligand-binding...

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書目詳細資料
Main Authors: Takagi, Junichi, Strokovich, Konstantin, Springer, Timothy A., Walz, Thomas
格式: Artigo
語言:Inglês
出版: Oxford University Press 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC212714/
https://ncbi.nlm.nih.gov/pubmed/12970173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg445
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