Structure of integrin α(5)β(1) in complex with fibronectin
The membrane-distal headpiece of integrins has evolved to specifically bind large extracellular protein ligands, but the molecular architecture of the resulting complexes has not been determined. We used molecular electron microscopy to determine the three-dimensional structure of the ligand-binding...
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| Опубликовано в:: | EMBO J |
|---|---|
| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC212714/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12970173/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg445 |
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