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Structure of integrin α(5)β(1) in complex with fibronectin

The membrane-distal headpiece of integrins has evolved to specifically bind large extracellular protein ligands, but the molecular architecture of the resulting complexes has not been determined. We used molecular electron microscopy to determine the three-dimensional structure of the ligand-binding...

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Podrobná bibliografie
Hlavní autoři: Takagi, Junichi, Strokovich, Konstantin, Springer, Timothy A., Walz, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC212714/
https://ncbi.nlm.nih.gov/pubmed/12970173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg445
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