Structure of integrin α(5)β(1) in complex with fibronectin

The membrane-distal headpiece of integrins has evolved to specifically bind large extracellular protein ligands, but the molecular architecture of the resulting complexes has not been determined. We used molecular electron microscopy to determine the three-dimensional structure of the ligand-binding...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Takagi, Junichi, Strokovich, Konstantin, Springer, Timothy A., Walz, Thomas
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2003
Assuntos:	Articles
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC212714/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12970173/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg445
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