Low-affinity integrin states have faster ligand-binding kinetics than the high-affinity state
Integrin conformational ensembles contain two low-affinity states, bent-closed and extended-closed, and an active, high-affinity, extended-open state. It is widely thought that integrins must be activated before they bind ligand; however, one model holds that activation follows ligand binding. As li...
保存先:
| 主要な著者: | , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
eLife Sciences Publications Ltd
2021-12-01
|
| シリーズ: | eLife |
| 主題: | |
| オンライン･アクセス: | https://elifesciences.org/articles/73359 |
| タグ: |
タグなし, このレコードへの初めてのタグを付けませんか!
|