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Energetics of side-chain snorkeling in transmembrane helices probed by nonproteinogenic amino acids
Cotranslational translocon-mediated insertion of membrane proteins into the endoplasmic reticulum is a key process in membrane protein biogenesis. Although the mechanism is understood in outline, quantitative data on the energetics of the process is scarce. Here, we have measured the effect on membr...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5035864/ https://ncbi.nlm.nih.gov/pubmed/27601675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1606776113 |
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