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Snorkeling Basic Amino Acid Side Chains Regulate Transmembrane Integrin Signalling
Side chains of Lys/Arg near transmembrane domain (TMD)(1–3) membrane-water interfaces can “snorkel” placing their positive charge near negatively-charged phospholipid head groups(4–6); however, snorkeling's functional effects are obscure. Integrin β TMDs exhibit such conserved basic amino acids...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3257387/ https://ncbi.nlm.nih.gov/pubmed/22178926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10697 |
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