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Interactions of platelet integrin α(ΙΙb) and β(3) transmembrane domains in mammalian cell membranes and their role in integrin activation
Clustering and occupancy of platelet integrin α(IIb)β(3) (GPIIb-IIIa) generate biologically important signals: conversely, intracellular signals increase the integrins' affinity, leading to integrin activation; both forms of integrin signaling play important roles in hemostasis and thrombosis....
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Hematology
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2680374/ https://ncbi.nlm.nih.gov/pubmed/19218549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-10-186551 |
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