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The structure of the integrin αIIbβ3 transmembrane complex explains integrin transmembrane signalling

Heterodimeric integrin adhesion receptors regulate cell migration, survival and differentiation in metazoa by communicating signals bi-directionally across the plasma membrane. Protein engineering and mutagenesis studies have suggested that the dissociation of a complex formed by the single-pass tra...

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Detalhes bibliográficos
Main Authors: Lau, Tong-Lay, Kim, Chungho, Ginsberg, Mark H, Ulmer, Tobias S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683045/
https://ncbi.nlm.nih.gov/pubmed/19279667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.63
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