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The structure of the integrin αIIbβ3 transmembrane complex explains integrin transmembrane signalling
Heterodimeric integrin adhesion receptors regulate cell migration, survival and differentiation in metazoa by communicating signals bi-directionally across the plasma membrane. Protein engineering and mutagenesis studies have suggested that the dissociation of a complex formed by the single-pass tra...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2683045/ https://ncbi.nlm.nih.gov/pubmed/19279667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.63 |
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