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Energetics of side-chain snorkeling in transmembrane helices probed by nonproteinogenic amino acids
Cotranslational translocon-mediated insertion of membrane proteins into the endoplasmic reticulum is a key process in membrane protein biogenesis. Although the mechanism is understood in outline, quantitative data on the energetics of the process is scarce. Here, we have measured the effect on membr...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5035864/ https://ncbi.nlm.nih.gov/pubmed/27601675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1606776113 |
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