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The extracellular role of DNA damage repair protein APE1 in regulation of IL-6 expression

The human apurinic/apyrimidinic endonuclease 1 (APE1) is a pleiotropic nuclear protein with roles in DNA base excision repair pathway as well as in regulation of transcription. Recently, the presence of extracellular plasma APE1 was reported in endotoxemic rats. However, the biological significance...

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Detalhes bibliográficos
Publicado no:Cell Signal
Main Authors: Nath, Somsubhra, Roychoudhury, Shrabasti, Kling, Matthew, Song, Heyu, Biswas, Pranjal, Shukla, Ashima, Band, Hamid, Joshi, Shantaram, Bhakat, Kishor K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5592147/
https://ncbi.nlm.nih.gov/pubmed/28751279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2017.07.019
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