Endogenous oxidized DNA bases and APE1 regulate the formation of G-quadruplex structures in the genome

Formation of G-quadruplex (G4) DNA structures in key regulatory regions in the genome has emerged as a secondary structure-based epigenetic mechanism for regulating multiple biological processes including transcription, replication, and telomere maintenance. G4 formation (folding), stabilization, an...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Roychoudhury, Shrabasti, Pramanik, Suravi, Harris, Hannah L., Tarpley, Mason, Sarkar, Aniruddha, Spagnol, Gaelle, Sorgen, Paul L., Chowdhury, Dipanjan, Band, Vimla, Klinkebiel, David, Bhakat, Kishor K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7260947/
https://ncbi.nlm.nih.gov/pubmed/32404420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1912355117
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