Nalaganje...
CCCTC-Binding Factor Locks Premature IgH Germline Transcription and Restrains Class Switch Recombination
In response to antigenic stimulation B cells undergo class switch recombination (CSR) at the immunoglobulin heavy chain (IgH) to replace the primary IgM/IgD isotypes by IgG, IgE, or IgA. CSR is initiated by activation-induced cytidine deaminase (AID) through the deamination of cytosine residues at t...
Shranjeno v:
| izdano v: | Front Immunol |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Frontiers Media S.A.
2017
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5591319/ https://ncbi.nlm.nih.gov/pubmed/28928744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01076 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|