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Class switch recombination in the absence of the IgH 3’ regulatory region
The ~28 kb 3′-regulatory region (3′RR) which is located at the most distal 3′ region of the immunoglobulin (Ig) heavy (H) chain locus has multiple regulatory functions that control IgH expression, class switch recombination (CSR) and somatic hypermutation (SHM). Here, we report that deletion of the...
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| Publicado no: | J Immunol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5026946/ https://ncbi.nlm.nih.gov/pubmed/27559052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600530 |
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