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Class switch recombination in the absence of the IgH 3’ regulatory region
The ~28 kb 3′-regulatory region (3′RR) which is located at the most distal 3′ region of the immunoglobulin (Ig) heavy (H) chain locus has multiple regulatory functions that control IgH expression, class switch recombination (CSR) and somatic hypermutation (SHM). Here, we report that deletion of the...
में बचाया:
| में प्रकाशित: | J Immunol |
|---|---|
| मुख्य लेखकों: | , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2016
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5026946/ https://ncbi.nlm.nih.gov/pubmed/27559052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600530 |
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