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The repetitive portion of the Xenopus IgH Mu switch region mediates orientation-dependent class switch recombination
Vertebrates developed immunoglobulin heavy chain (IgH) class switch recombination (CSR) to express different IgH constant regions. Most double-strand breaks for Ig CSR occur within the repetitive portion of the switch regions located upstream of each set of constant domain exons for the Igγ, Igα or...
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| Publié dans: | Mol Immunol |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4615597/ https://ncbi.nlm.nih.gov/pubmed/26277278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2015.07.039 |
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