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The repetitive portion of the Xenopus IgH Mu switch region mediates orientation-dependent class switch recombination

Vertebrates developed immunoglobulin heavy chain (IgH) class switch recombination (CSR) to express different IgH constant regions. Most double-strand breaks for Ig CSR occur within the repetitive portion of the switch regions located upstream of each set of constant domain exons for the Igγ, Igα or...

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Bibliografische gegevens
Gepubliceerd in:Mol Immunol
Hoofdauteurs: Zhang, Zheng Z., Pannunzio, Nicholas R., Lu, Zhengfei, Hsu, Ellen, Yu, Kefei, Lieber, Michael R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615597/
https://ncbi.nlm.nih.gov/pubmed/26277278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2015.07.039
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