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CURRENT INSIGHTS INTO THE MECHANISM OF MAMMALIAN IMMUNOGLOBULIN CLASS SWITCH RECOMBINATION
Immunoglobulin Class switch recombination (CSR) is the gene rearrangement process by which B lymphocytes change the immunoglobulin (Ig) heavy chain constant region to permit a switch of Ig isotype from IgM to IgG, IgA, or IgE. At the DNA level, CSR occurs via generation and joining of DNA double str...
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| Pubblicato in: | Crit Rev Biochem Mol Biol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6856442/ https://ncbi.nlm.nih.gov/pubmed/31509023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10409238.2019.1659227 |
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