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Downstream boundary of chromosomal R-loops at murine switch regions: Implications for the mechanism of class switch recombination

R-loops form at Sγ3 and Sγ2b Ig class switch regions in the chromosomes of stimulated murine primary B cells and are suspected to be a general feature of mammalian class switch regions. The in vivo upstream boundary of the R-loops is known to begin within the switch repeats. To determine how precise...

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Detalhes bibliográficos
Principais autores: Huang, Feng-Ting, Yu, Kefei, Hsieh, Chih-Lin, Lieber, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458789/
https://ncbi.nlm.nih.gov/pubmed/16547142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506548103
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