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Effect of CpG Dinucleotides within IgH Switch Region Repeats on Immunoglobulin Class Switch Recombination
Immunoglobulin (Ig) heavy chains undergo class switch recombination (CSR) to change the heavy chain isotype from IgM to IgG, A or E. The switch regions are several kilobases long, repetitive, and G-rich on the nontemplate strand. They are also relatively depleted of CpG (also called CG) sites for un...
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| Veröffentlicht in: | Mol Immunol |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4461542/ https://ncbi.nlm.nih.gov/pubmed/25899867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2015.04.005 |
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