Sequence Dependence of Chromosomal R-Loops at the Immunoglobulin Heavy-Chain Sμ Class Switch Region

The mechanism by which the cytidine deaminase activation-induced deaminase (AID) acts at immunoglobulin heavy-chain class switch regions during mammalian class switch recombination (CSR) remains unclear. R-loops have been proposed as a basis for this targeting. Here, we show that the difference betw...

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Main Authors: Huang, Feng-Ting, Yu, Kefei, Balter, Barbara B., Selsing, Erik, Oruc, Zeliha, Khamlichi, Ahmed Amine, Hsieh, Chih-Lin, Lieber, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1952116/
https://ncbi.nlm.nih.gov/pubmed/17562862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00702-07
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