Sequence Dependence of Chromosomal R-Loops at the Immunoglobulin Heavy-Chain Sμ Class Switch Region

The mechanism by which the cytidine deaminase activation-induced deaminase (AID) acts at immunoglobulin heavy-chain class switch regions during mammalian class switch recombination (CSR) remains unclear. R-loops have been proposed as a basis for this targeting. Here, we show that the difference betw...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Huang, Feng-Ting, Yu, Kefei, Balter, Barbara B., Selsing, Erik, Oruc, Zeliha, Khamlichi, Ahmed Amine, Hsieh, Chih-Lin, Lieber, Michael R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2007
Materias:
Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1952116/
https://ncbi.nlm.nih.gov/pubmed/17562862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00702-07
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares