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Mechanism of R-Loop Formation at Immunoglobulin Class Switch Sequences
R-loops have been described in vivo at the immunoglobulin class switch sequences and at prokaryotic and mitochondrial origins of replication. However, the biochemical mechanism and determinants of R-loop formation are unclear. We find that R-loop formation is nearly eliminated when RNase T(1) is add...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2223306/ https://ncbi.nlm.nih.gov/pubmed/17954560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01251-07 |
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