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Complete cis Exclusion upon Duplication of the Eμ Enhancer at the Immunoglobulin Heavy Chain Locus

Developing lymphocytes somatically diversify their antigen-receptor loci through V(D)J recombination. The process is associated with allelic exclusion, which results in monoallelic expression of an antigen receptor locus. Various cis-regulatory elements control V(D)J recombination in a developmental...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Puget, Nadine, Leduc, Claire, Oruc, Zéliha, Moutahir, Mohammed, Le Bert, Marc, Khamlichi, Ahmed Amine
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456450/
https://ncbi.nlm.nih.gov/pubmed/25896912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00294-15
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