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HIV-1-mediated insertional activation of STAT5B and BACH2 trigger viral reservoir in T regulatory cells
HIV-1 insertions targeting BACH2 or MLK2 are enriched and persist for decades in hematopoietic cells from patients under combination antiretroviral therapy. However, it is unclear how these insertions provide such selective advantage to infected cell clones. Here, we show that in 30/87 (34%) patient...
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| 發表在: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5591266/ https://ncbi.nlm.nih.gov/pubmed/28887441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00609-1 |
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