Lentiviral Vector-based Insertional Mutagenesis Identifies Genes Involved in the Resistance to Targeted Anticancer Therapies

The high transduction efficiency of lentiviral vectors in a wide variety of cells makes them an ideal tool for forward genetics screenings addressing issues of cancer research. Although molecular targeted therapies have provided significant advances in tumor treatment, relapses often occur by the ex...

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Bibliografiske detaljer
Udgivet i:Mol Ther
Main Authors: Ranzani, Marco, Annunziato, Stefano, Calabria, Andrea, Brasca, Stefano, Benedicenti, Fabrizio, Gallina, Pierangela, Naldini, Luigi, Montini, Eugenio
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429698/
https://ncbi.nlm.nih.gov/pubmed/25195596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.174
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