Lentiviral Vector-based Insertional Mutagenesis Identifies Genes Involved in the Resistance to Targeted Anticancer Therapies

The high transduction efficiency of lentiviral vectors in a wide variety of cells makes them an ideal tool for forward genetics screenings addressing issues of cancer research. Although molecular targeted therapies have provided significant advances in tumor treatment, relapses often occur by the ex...

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Dettagli Bibliografici
Pubblicato in:Mol Ther
Autori principali: Ranzani, Marco, Annunziato, Stefano, Calabria, Andrea, Brasca, Stefano, Benedicenti, Fabrizio, Gallina, Pierangela, Naldini, Luigi, Montini, Eugenio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429698/
https://ncbi.nlm.nih.gov/pubmed/25195596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.174
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