Lentiviral Vector-based Insertional Mutagenesis Identifies Genes Involved in the Resistance to Targeted Anticancer Therapies

The high transduction efficiency of lentiviral vectors in a wide variety of cells makes them an ideal tool for forward genetics screenings addressing issues of cancer research. Although molecular targeted therapies have provided significant advances in tumor treatment, relapses often occur by the ex...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Ranzani, Marco, Annunziato, Stefano, Calabria, Andrea, Brasca, Stefano, Benedicenti, Fabrizio, Gallina, Pierangela, Naldini, Luigi, Montini, Eugenio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429698/
https://ncbi.nlm.nih.gov/pubmed/25195596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.174
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