γ-TRIS: a graph-algorithm for comprehensive identification of vector genomic insertion sites

SUMMARY: Retroviruses and their vector derivatives integrate semi-randomly in the genome of host cells and are inherited by their progeny as stable genetic marks. The retrieval and mapping of the sequences flanking the virus-host DNA junctions allows the identification of insertion sites in gene the...

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Bibliographic Details
Published in:Bioinformatics
Main Authors: Calabria, Andrea, Beretta, Stefano, Merelli, Ivan, Spinozzi, Giulio, Brasca, Stefano, Pirola, Yuri, Benedicenti, Fabrizio, Tenderini, Erika, Bonizzoni, Paola, Milanesi, Luciano, Montini, Eugenio
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7703754/
https://ncbi.nlm.nih.gov/pubmed/31589304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz747
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