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VISPA2: a scalable pipeline for high-throughput identification and annotation of vector integration sites

BACKGROUND: Bioinformatics tools designed to identify lentiviral or retroviral vector insertion sites in the genome of host cells are used to address the safety and long-term efficacy of hematopoietic stem cell gene therapy applications and to study the clonal dynamics of hematopoietic reconstitutio...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Spinozzi, Giulio, Calabria, Andrea, Brasca, Stefano, Beretta, Stefano, Merelli, Ivan, Milanesi, Luciano, Montini, Eugenio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5702242/
https://ncbi.nlm.nih.gov/pubmed/29178837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1937-9
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