VISPA: a computational pipeline for the identification and analysis of genomic vector integration sites

The analysis of the genomic distribution of viral vector genomic integration sites is a key step in hematopoietic stem cell-based gene therapy applications, allowing to assess both the safety and the efficacy of the treatment and to study the basic aspects of hematopoiesis and stem cell biology. Ide...

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Autores principales: Calabria, Andrea, Leo, Simone, Benedicenti, Fabrizio, Cesana, Daniela, Spinozzi, Giulio, Orsini, Massimilano, Merella, Stefania, Stupka, Elia, Zanetti, Gianluigi, Montini, Eugenio
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169225/
https://ncbi.nlm.nih.gov/pubmed/25342980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-014-0067-5
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