Lentiviral vector-based insertional mutagenesis identifies genes associated with liver cancer

Transposons and γ-retroviruses have been efficiently used as insertional mutagens in different tissues to identify molecular culprits of cancer. However, these systems are characterized by recurring integrations that accumulate in tumor cells, hampering the identification of early cancer-driving eve...

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Detalhes bibliográficos
Principais autores: Ranzani, Marco, Cesana, Daniela, Bartholomae, Cynthia C., Sanvito, Francesca, Pala, Mauro, Benedicenti, Fabrizio, Gallina, Pierangela, Sergi, Lucia Sergi, Merella, Stefania, Bulfone, Alessandro, Doglioni, Claudio, von Kalle, Christof, Kim, Yoon Jun, Schmidt, Manfred, Tonon, Giovanni, Naldini, Luigi, Montini, Eugenio
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589714/
https://ncbi.nlm.nih.gov/pubmed/23314173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2331
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