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Lentiviral vector-based insertional mutagenesis identifies genes associated with liver cancer

Transposons and γ-retroviruses have been efficiently used as insertional mutagens in different tissues to identify molecular culprits of cancer. However, these systems are characterized by recurring integrations that accumulate in tumor cells, hampering the identification of early cancer-driving eve...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Ranzani, Marco, Cesana, Daniela, Bartholomae, Cynthia C., Sanvito, Francesca, Pala, Mauro, Benedicenti, Fabrizio, Gallina, Pierangela, Sergi, Lucia Sergi, Merella, Stefania, Bulfone, Alessandro, Doglioni, Claudio, von Kalle, Christof, Kim, Yoon Jun, Schmidt, Manfred, Tonon, Giovanni, Naldini, Luigi, Montini, Eugenio
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2013
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589714/
https://ncbi.nlm.nih.gov/pubmed/23314173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2331
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