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The C-terminal residue of phage Vp16 PDF, the smallest peptide deformylase, acts as an offset element locking the active conformation

Prokaryotic proteins must be deformylated before the removal of their first methionine. Peptide deformylase (PDF) is indispensable and guarantees this mechanism. Recent metagenomics studies revealed new idiosyncratic PDF forms as the most abundant family of viral sequences. Little is known regarding...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Grzela, Renata, Nusbaum, Julien, Fieulaine, Sonia, Lavecchia, Francesco, Bienvenut, Willy V., Dian, Cyril, Meinnel, Thierry, Giglione, Carmela
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5591237/
https://ncbi.nlm.nih.gov/pubmed/28887476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11329-3
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