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Identification of eukaryotic peptide deformylases reveals universality of N-terminal protein processing mechanisms
The N-terminal protein processing pathway is an essential mechanism found in all organisms. However, it is widely believed that deformylase, a key enzyme involved in this process in bacteria, does not exist in eukaryotes, thus making it a target for antibacterial agents such as actinonin. In an atte...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
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Oxford University Press
2000
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC305796/ https://ncbi.nlm.nih.gov/pubmed/11060042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.21.5916 |
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